Cytoskeleton and Golgi-apparatus interactions: A two-way road of function and structure

摘要

The Golgi apparatus is the result of a complex and dynamic interaction between a\udlarge variety of molecules that determine its architecture, protein and lipid transports, and those\udthat integrate signals from outside and inside the cell. The cytoskeleton facilitates the functional\udintegration of all these processes. Association and coordination between microtubules and actin\udfilaments, as well as their respective binding and regulatory proteins, are clearly necessary for\udGolgi structure and function. Protein sorting, membrane fission and fusion, and the motion of\udGolgi-derived transport carriers are all affected by both cytoskeleton elements